Emerging biomarkers for early detection of diseases (e.g., Alzheimer's, cardiac conditions)
DOI:
https://doi.org/10.63278/jicrcr.vi.975Keywords:
Amyloid-beta (Aβ), Tau protein, Neurofilament light chain (NfL), High-sensitivity troponin (hs-Tn), N-terminal pro-B-type natriuretic peptide (NT-proBNP) and C-reactive protein (CRP)Abstract
Background: Biomarkers are quantifiable biological signs that offer vital details about a person's health or illness. Finding new biomarkers for the early diagnosis of illnesses like Alzheimer's and cardiovascular disorders has drawn more attention in recent years. Improving patient outcomes, enabling prompt management, and slowing the progression of the disease all depend on early detection. Early diagnosis and tailored medicine have been transformed by the identification of novel biomarkers made possible by developments in molecular biology, proteomics, and imaging techniques. These new biomarkers, which have the potential to revolutionize diagnostics, include blood-based markers, genetic variations, and imaging-based indicators.
Aim: This study aims to identify and evaluate emerging biomarkers for early detection of Alzheimer's disease and cardiac conditions, understand their mechanisms and clinical relevance, and assess their potential impact on improving diagnostic accuracy and patient outcomes.
Conclusion: A new era in the early detection of diseases such as Alzheimer's and heart issues is dawning, made possible by emerging biomarkers. There is a lot of hope for the therapeutic use of biomarkers like NT-proBNP and amyloid-beta for cardiovascular disorders and tau and amyloid-beta for Alzheimer's. Nevertheless, there are still obstacles to overcome, such as accessibility, cost-effectiveness, and uniformity. If these biomarkers are to become standard in clinical practice, further study and validation of them are required. These innovations have the potential to make healthcare more efficient worldwide by lowering the illness burden, improving patient quality of life, and allowing early detection.