Patterns of Antimicrobial Resistance in Clinical Isolates at King Khaled Hospital, Najran, Saudi Arabia: An Analysis of Methicillin-Resistant Staphylococcus aureus, Carbapenem Resistance Enterobacteriaceae, Extended-Spectrum Beta-Lactamases, and Colistin

Mohsen Almakrami, Mohammed Salmen, Yahya Ahmad Aldashel, Mesfer Hussain Alyami, Nasser Alquraishah, Mohammad AlZureea, Jafar Almakrami; Zaid Alqureshah, Ghaitha Saad Alyami, Saleh Ahmed Alyami, Ali Hamad AlMsaad, Zaid Yahya Al quraisha, Mushabbab Alabbas, Hadi Alswar

doi:10.63278/jicrcr.v7i2.886

Patterns of Antimicrobial Resistance in Clinical Isolates at King Khaled Hospital, Najran, Saudi Arabia: An Analysis of Methicillin-Resistant Staphylococcus aureus, Carbapenem Resistance Enterobacteriaceae, Extended-Spectrum Beta-Lactamases, and Colistin

Authors

Mohsen Almakrami, Mohammed Salmen, Yahya Ahmad Aldashel, Mesfer Hussain Alyami, Nasser Alquraishah, Mohammad AlZureea, Jafar Almakrami
Zaid Alqureshah, Ghaitha Saad Alyami, Saleh Ahmed Alyami, Ali Hamad AlMsaad, Zaid Yahya Al quraisha, Mushabbab Alabbas, Hadi Alswar

DOI:

https://doi.org/10.63278/jicrcr.v7i2.886

Abstract

Antimicrobial resistance (AMR) is a substantial threat in Saudi Arabia. We focus on Methicillin-Resistant S. aureus (MRSA), carbapenem-resistant strains, Extended-Spectrum Beta-Lactamases (ESBL) producers, and colistin-resistance. We analyzed 559 samples (blood, urine, wound specimens). ESBLs were the most prevalent (55%), followed by MRSA (22%), combined ESBL and CRE resistance (18%). The ESBL phenotype had a colistin resistance of 71.3%, while ESBL and CRE phenotypes had 22.9%, and CRE had 5.8%. The age group 50+ had 58.7% resistance phenotypes. Urine samples had 49% prevalence of resistant phenotypes, while the highest rate according to ward location was at the OPD (55.8%).
The study highlights critical trends of AMR, emphasizing the urgency to antibiotic regulations, professional development for healthcare professionals, and local studies on AMR for targeted intervention.

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Published

2024-11-11

How to Cite

Mohsen Almakrami, Mohammed Salmen, Yahya Ahmad Aldashel, Mesfer Hussain Alyami, Nasser Alquraishah, Mohammad AlZureea, Jafar Almakrami, & Zaid Alqureshah, Ghaitha Saad Alyami, Saleh Ahmed Alyami, Ali Hamad AlMsaad, Zaid Yahya Al quraisha, Mushabbab Alabbas, Hadi Alswar. (2024). Patterns of Antimicrobial Resistance in Clinical Isolates at King Khaled Hospital, Najran, Saudi Arabia: An Analysis of Methicillin-Resistant Staphylococcus aureus, Carbapenem Resistance Enterobacteriaceae, Extended-Spectrum Beta-Lactamases, and Colistin . Journal of International Crisis and Risk Communication Research , 7(2), 249–264. https://doi.org/10.63278/jicrcr.v7i2.886