GLP-1 Treatment Potential Indication in Obese patients: Review of Adverse Effects and Efficacy
DOI:
https://doi.org/10.63278/jicrcr.vi.540Keywords:
Glucagon-like peptide-1 receptor agonists, obesity.Abstract
Obesity is a chronic, multifactorial disease linked to various comorbidities, including cardiovascular disease, diabetes, and certain cancers. Traditional management approaches such as lifestyle modifications often fail to produce sustainable results, necessitating pharmacological interventions. Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), initially approved for glycemic control in type 2 diabetes, have emerged as effective agents for weight management. This review evaluates the efficacy of GLP-1 RAs, including semaglutide and liraglutide, in promoting weight loss and improving metabolic health in obese patients. The paper also examines the adverse effects associated with their use and discusses potential strategies for optimizing their role in obesity treatment.




