Comparison of treatments for Pediatric asthma; A systematic review

Abstract

Background:
Asthma is an airway inflammatory illness of persistent nature. It is distinguished by mucus plugging wheezing episodes, cough and breath shortness. It is the most prevalent persistent respiratory illness of childhood. Poor control of asthma is linked with several consequences, including severe symptoms and life-threatening attacks. There are various pharmacological therapeutic options for the management of asthmatic children.
Aim:
To compare the outcomes of different pediatric asthma treatments by examining the research focused on this topic.
Methods:
Searching through the scientific databases and using many terms was done to obtain relevant studies. The exploration procedure focused on original pediatric studies written in English language and available for full text comparing different asthma
treatment with inhaled corticosteroids.

Results:
Eight studies were the final number of research enrolled in this review. The extracted data was summarized under major titles. A total of 1360 children were included and several medications were reported, including short and long acting
beta-agonists, omalizumab, montelukast and theophylline.
Conclusion:
Combination regimen of ICS with other asthmatic therapies seems to provide better control of asthma among the pediatric subjects compared to monotherapy. Furthermore, the combination therapy led to ICS dose reduction. The selection ofthe best regimen is dependent on several factors that should be considered before the adoption of a definite therapeutic regimen.