A retrospective study to evaluate the effect of Laparoscopic sleeve gastrectomy on Type 2 Diabetic Morbid Obese patients by comparing HbA1c levels before and after surgery
DOI:
https://doi.org/10.63278/jicrcr.vi.2556Abstract
Background and Objectives: Morbid obesity is a significant risk factor for type 2 diabetes. Bariatric surgery improves glycemic control in obese individuals. Laparoscopic sleeve gastrectomy (LSG) is a commonly performed bariatric procedure. This retrospective study evaluated the effect of laparoscopic sleeve gastrectomy (LSG) on glycaemic control in morbidly obese patients with prediabetes and diabetes by comparing pre- and post-surgery hemoglobin A1c (HbA1c) levels.
Methods: This retrospective study analysed data from morbidly obese patients who underwent LSG at the Emirates Health Services, Khorfakkan Hospital in Sharjah Emirate of the United Arab Emirates between January 2018 and January 2023 by analysing blood pressure, lipid profiles, and blood sugar levels during pre- and post-surgery.
Results: This study included 156 patients who had a mean age of 30.46 ± 9.9 years and predominantly were female (64.7%). The majority of the patients (70.5%) had no comorbidities. The mean blood pressure was 121.41 ± 13.22 mmHg systolic and 70.718 ± 10.34 mmHg diastolic. Lipid profiles showed mean total cholesterol of 4.873 ± 0.90 mmol/L, triglycerides of 1.249 ± 0.72 mmol/L, and HDL of 1.225 ± 0.28 mmol/L. Mean random blood sugar was 6.186 ± 2.67 mmol/L, and mean hospital stay was 2.436 ± 0.95 days. After the surgery, the mean weight loss significantly decreased from 96.37 kg to 78.77 kg (p = 0.001). There were significant reductions in HbA1c levels across all patient groups: non-diabetic patients showed a mean decrease of 0.174 (p = 0.01), pre-diabetic patients a mean decrease of 0.671 (p = 0.001), and diabetic patients a mean decrease of 1.99 (p-value = 0.005) after 6 months post-surgery.
Conclusion: This study demonstrated that LSG is associated with significant improvements in glycaemic control in morbidly obese patients with prediabetes and diabetes, as evidenced by reductions in HbA1c levels.
