The impact of epilepsy surgery on seizure among adults; A systematic review

Abstract

Background: Epilepsy is a chronic neurological illness that has deleterious impacts on vocational, physical, social, and psychological well-being. Epileptic patients are at increased risk of experiencing unprovoked seizures which are the primary cause of epilepsy-related disability, mortality, and morbidity. Epilepsy surgery is the alternative approach for the management of seizures in case of failure of antiseizure medications. The primary goal of epilepsy surgery is seizure freedom.
Aim: To assess the impact of epilepsy surgery on seizure outcomes among adult patients by reviewing the previous original literature that evaluated such a subject.
Methods: Exploration of PubMed, Springer, Scopus, Science Direct, and Google Scholar was done to obtain related studies. Studies published between 2015 and 2024 were eligible. Original English articles that reported seizure outcomes following surgical management of epilepsy and focused on the adult population were considered eligible articles and included in the review.
Results: Eight studies were included in agreement with eligible criteria; they included 1422 patients with an age range of 17-70 years duration of epilepsy ranged between zero to 59 years and follow-up duration ranged between one year and 27 years.
Conclusion: Epilepsy surgery is a good approach for the management of epilepsy with the achievement of seizure-free under the condition of an appropriate selection of patients and an appropriate selection of surgical approach as well as precise pre-surgical evaluation.