Impact of vitamin D supplementation on the glycemic control of pre-diabetic individuals

Abstract

Vitamin D supplementation has garnered attention for its potential role in glycemic control, particularly among pre-diabetic individuals. Research indicates that vitamin D influences insulin secretion and sensitivity, which are crucial for maintaining normal glucose metabolism. Low levels of vitamin D have been associated with insulin resistance, a key factor in the progression from pre-diabetes to type 2 diabetes. Several studies suggest that adequate vitamin D levels can improve insulin sensitivity and may help lower fasting glucose levels, thereby supporting better glycemic control in those at risk of developing diabetes. However, the effectiveness of vitamin D supplementation can vary among individuals, influenced by factors such as baseline vitamin D status, ethnicity, and lifestyle choices. While some trials have reported significant improvements in glycemic markers following supplementation, others have shown negligible effects. This inconsistency underscores the necessity for further research to delineate the optimal dosage, duration, and population characteristics that could maximize the benefits of vitamin D for glycemic control in pre-diabetic individuals. As such, healthcare providers may consider evaluating vitamin D levels in pre-diabetic patients and assessing the potential benefits of supplementation as part of a comprehensive approach to diabetes prevention.