"The Role of Theoretical Toxicology in Shaping Future Diagnostic Approaches in Medical Laboratories"

Abstract

This study explores the role of theoretical toxicology in advancing diagnostic approaches in medical laboratories. The methodology integrates experimental analysis, computational modeling, and bioinformatics to address toxicological challenges. Using tools like GC-MS and HPLC, the research achieved high sensitivity in detecting toxicants in clinical samples. Computational predictions were validated against clinical observations, demonstrating over 94% agreement for toxicants such as lead, acetaminophen, and pesticides. Additionally, gene expression analysis identified key toxicity pathways, including oxidative stress and apoptosis, offering insights into molecular mechanisms. The results affirm the reliability of combining computational and experimental toxicology for precision diagnostics, paving the way for improved safety assessments and personalized medicine.