Nanotechnology in Drug Delivery: Overcoming Biological Barriers and Enhancing Targeted Therapy

Abstract

Background:Nanotechnology is revolutionizing the pharmaceutical sciences by providing new ways to deliver drugs to the body. Drugs can have their bioavailability, solubility, and targeting capabilities improved with the use of nanoparticles and other nanoscale materials. New drug delivery systems made possible by nanotechnology have the potential to enhance therapeutic results while reducing unwanted side effects. Doxil® and Abraxane® are just two of the many FDA-approved nanomedicines that highlight how this technology has the potential to transform conventional medicine for the treatment of cancer, neurological disorders, and infectious diseases.
Aim:To better understand how to construct nanoparticles and nanocarriers to increase therapeutic efficacy, decrease toxicity, and offer more controlled and targeted distribution to tissues or cells, researchers are investigating the use of nanotechnology in drug delivery. Research into targeted drug delivery methods, assessments of nanomedicines' therapeutic potential, and resolution of issues related to the development and implementation of therapies based on nanotechnology are all part of this field. Further, we hope to bring attention to the promising future of nanomedicine by showcasing its potential applications in areas such as sustainable and individualized healthcare, the use of biodegradable materials, and the integration of artificial intelligence.
Conclusion:By allowing for more efficient, accurate, and tailored therapeutics, nanotechnology may completely alter drug delivery methods. Improved medication solubility, bioavailability, and therapeutic effectiveness with reduced systemic toxicity and adverse effects are all possible thanks to nanomedicines, which are made possible by advancements in nanoparticle design and drug encapsulation. Future answers for sustainable and personalized treatment may lie in the integration of artificial intelligence, advancements in biodegradable materials, and the creation of multifunctional theranostic nanocarriers, despite obstacles including high development costs and safety concerns. Researchers are hopeful that nanotechnology will usher in a new age of highly targeted, efficient, and less intrusive medicines, vastly improving treatment outcomes for a variety of ailments.