Exploring the link between periodontal disease and dementia in aging populations; Review

Abstract

Periodontal disease and dementia are prevalent conditions in aging populations, with emerging evidence suggesting a potential link between the two. Chronic inflammation and bacterial dissemination associated with periodontal disease contribute to systemic and neuroinflammation, which are implicated in the pathogenesis of dementia, including Alzheimer’s disease. Shared risk factors, such as aging, diabetes, and cardiovascular disease, further connect these conditions. This review explores the relationship between periodontal disease and dementia, highlighting shared mechanisms, epidemiological evidence, and implications for prevention. Integrating oral health into geriatric care and addressing periodontal disease as a modifiable risk factor could offer new avenues for mitigating cognitive decline in older adults.